We have collaborated with the Sheffield Clinical Trials Research Unit to support them with the management of data for clinical studies. Together we have developed SCRAM as a secure online platform to allow site and clinical staff to randomise participants on clinical studies, and for study teams to report on those allocations throughout the study.
SCRAM supports simple list-based randomisation, as well as minimisation to support studies with smaller user counts. Where needed, studies can be configured to use stratification, unequal intervention allocations, and multiple phases. We support open and double-blind studies, as well as emergency unblinding functionality. SCRAM can also be configured to notify relevant staff when a randomisation or an emergency unblinding occurs, and features comprehensive activity logging and audit trails.
SCRAM is fully web-based and centrally hosted, meaning that there is no need for installation of software at participating study sites; all that is needed is access to the internet through a modern web browser.
Our electronic data capture (EDC) system is focused on the capture and management of data for clinical studies, either by transcription from paper CRFs or from direct data entry by designated site staff. In development since 2009, through close collaboration with the Clinical Trials Research Unit at the University of Sheffield, our system has supported over 50 studies.
If you would like to ask a question about our Randomisation and Minimisation System (SCRAM) or request a demo, please contact us and a member of our team will be happy to help.